Entry courtesy of
The National Human Genome Research Institute (NHGRI)

Mouse model

A laboratory mouse useful for medical research because it has specific characteristics that resemble a human disease or disorder. Strains of mice having natural mutations similar to human ones may serve as models of such conditions. Scientists can also create mouse models by transferring new genes into mice or by inactivating certain existing genes in them.

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Dr. Anthony Wynshaw-Boris, of the National Human Genome Research Institute's Laboratory of Genetic Disease Research, defines mouse model.