Entry courtesy of
The National Human Genome Research Institute (NHGRI)

BRCA1/BRCA2

The first breast cancer genes to be identified. Mutated forms of these genes are believed to be responsible for about half the cases of inherited breast cancer, especially those that occur in younger women. Both are tumor suppressor genes.

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Dr. Lawrence Brody, of the National Human Genome Research Institute's Genetic and Molecular Biology Branch, defines BRCA1/BRCA2.